The Universe is Open
Reductionism has reigned as our dominant world view for 350 years in Western society. Physicist Steven Weinberg states that when the science shall have been done, all the explanatory arrows will point downward, from societies to people, to organs, to cells, to biochemistry, to chemistry and ultimately to physics and the final theory.
I think he is wrong: the evolution of the biosphere, the economy, our human culture and perhaps aspects of the abiotic world, stand partially free of physical law and are not entailed by fundamental physics. The universe is open.
Reductionism is doing less and less for me as time goes by. An open, strange and mysterious universe is way more exciting than a nailed-down, well-defined one. (Incidentally, I'm coming to think that, in its way, religion is as reductionist as science.)